Hi Sir/Madam,
I am currently testing out the VEP program that was download from (https://github.com/Ensembl/ensembl-tools/archive/release/84.zip).
The VEP program ran to completion and generate reasonable outputs (including ExAC frequencies). However, I noticed that I am getting the following repeated error lines:
Plugin 'ExAC' went wrong: Illegal division by zero at /root/vep/Plugins/ExAC.pm line 253, line 2.
Plugin 'ExAC' went wrong: Illegal division by zero at /root/vep/Plugins/ExAC.pm line 253, line 4.
Plugin 'ExAC' went wrong: Illegal division by zero at /root/vep/Plugins/ExAC.pm line 253, line 6.
Plugin 'ExAC' went wrong: Illegal division by zero at /root/vep/Plugins/ExAC.pm line 253, line 8.
Plugin 'ExAC' went wrong: Illegal division by zero at /root/vep/Plugins/ExAC.pm line 253, line 10.
Plugin 'ExAC' went wrong: Illegal division by zero at /root/vep/Plugins/ExAC.pm line 253, line 1.
Plugin 'ExAC' went wrong: Illegal division by zero at /root/vep/Plugins/ExAC.pm line 253, line 2.
Plugin 'ExAC' went wrong: Illegal division by zero at /root/vep/Plugins/ExAC.pm line 253, line 3.
Plugin 'ExAC' went wrong: Illegal division by zero at /root/vep/Plugins/ExAC.pm line 253, line 4.
Plugin 'ExAC' went wrong: Illegal division by zero at /root/vep/Plugins/ExAC.pm line 253, line 5.
Plugin 'ExAC' went wrong: Illegal division by zero at /root/vep/Plugins/ExAC.pm line 253, line 6.
Plugin 'ExAC' went wrong: Illegal division by zero at /root/vep/Plugins/ExAC.pm line 253, line 7.
Is this is something I should be worried about?
The input VCF coordinates are in GRCh37 reference. I obtained the ExAC resource files from https://googledrive.com/host/0B6o74flPT8FAYnBJTk9aTF9WVnM and then used tabix v0.2.6 to create the *.tbi file.
I can provide more information/data to reproduce this error if needed.