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Framework to process and call somatic variation from NGS dataset generated using MSK-IMPACT assay

Home Page: http://impact-pipeline.readthedocs.org/en/latest/index.html

License: Apache License 2.0

Perl 63.12% Python 5.80% R 1.80% Shell 0.25% Makefile 0.66% Batchfile 0.65% CSS 2.14% JavaScript 8.95% HTML 16.64%
ngs cancer-genomics precision-medicine cancer-variants illumina-sequencing mskimpact msk-impact

impact-pipeline's Introduction

Danger

This codebase is deprected and is no maintained/used in its current form.

IMPACT-Pipeline: MSK-IMPACT assay data analysis framework to process data on LSF/SGE

Author

Ronak H Shah, Donavan Cheng, Ahmet Zehir, Aijazuddin Syed, Raghu Chandramohan, Meera Prasad et.al

Contact

[email protected]

Source code

http://github.com/rhshah/IMPACT-Pipeline

Wiki

http://impact-pipeline.readthedocs.org/en/latest/index.html

License

Apache License 2.0

IMPACT-Pipeline is a Perl/Python/R command-line software toolkit to process data, call somatic aberrations (SNV,INDELS,SV,CNV) generated by NGS based MSK-IMPACT assay. It is designed for use with hybrid capture, including both whole-exome and custom target panels, and short-read sequencing platforms such as Illumina.

For Description/Usage/Help:

Please visit here: IMPACT-Pipeline Wiki

Citation

If you use this software in a publication, please cite our paper

Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology.

for code citation use:

image

impact-pipeline's People

Contributors

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impact-pipeline's Issues

Can't open /home/xxx/IMPACT_central.log (No such file or directory)

When I run this script that returned an exception to me.

Can't open /home/xxx/IMPACT_central.log (No such file or directory) at /IMPACT-Pipeline-1.0.1/sofeware/localperl/lib/site_perl/5.20.2/Log/Log4perl/Appender/File.pm line 151.
BEGIN failed--compilation aborted at /data/PRO/pro_cancer/pipeline/IMPACT-Pipeline-1.0.1/bin/RunIlluminaProcess.pl line 111.

As you know, a part of Linux systems set $HOME not equal '/home/yourname/'. I found the bug in the below script.

fix below:

my $uName = `echo \$HOME`;

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