interoperability with vg - error:[vg::SmallSnarlSimplifier] Invalid graph on iteration 0 about pggb HOT 14 OPEN

I think vg simplify being too old is probably at the root of this particular issue. Please raise an issue on the vg github and we can ask its author @adamnovak if you can even expect it to help you here (probably not).

In general, we want vg to be fully compatible with PGGB. The main issue now (as you're aware, I'm sure) is that the topologies coming out of PGGB are often too complex for vg to index and/or map to effectively. Hopefully there'll be some progress on this in the coming months (it's on all our radars). Unfortunately I don't think vg simplify, at least in its current state, is the answer. Apart from this issue with mapping, all the vg tools should work (ie for graph maninpulation and stats) should work with PGGB graphs (related - vg can operate directly on GFA without explicitly needing to convert).

from pggb.