Framework for the Inference of in Situ Interaction Kinetics from single-molecule imaging data with sub-stoichiometric labeling
FISIK is a stochastic mathematical modeling and model calibration framework (written in Matlab) that is designed to predict the full population interaction kinetics from the subset of interactions observed via single-molecule imaging with sub-stoichiometric labeling.
For more information, please see de Oliveira and Jaqaman, Biophys. J. 2019. FISIK: Framework for the Inference of in Situ Interaction Kinetics from single-molecule imaging data. https://pubmed.ncbi.nlm.nih.gov/31443908/.