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suez's Introduction

This code is associated with the paper from Knowles et al., "Determining the genetic basis of anthracycline-cardiotoxicity by molecular response QTL mapping in induced cardiomyocytes". eLife, 2018. http://dx.doi.org/10.7554/eLife.33480

suez: an R package for mapping response-eQTLs

suez extends the PANAMA eQTL mapping framework (http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1002330) to handle

  • multiple conditions (e.g. stimulated/unstimulated), including response-eQTL mapping
  • latent factor correction
  • known kinship between individuals

Installation

The easiest way to install is

if (!require("devtools")) install.packages("devtools", repos='http://cran.us.r-project.org')
devtools::install_github("davidaknowles/suez")

Usage

For example usage see here.

suez's People

Contributors

davidaknowles avatar editorialelife avatar

Watchers

James Cloos avatar

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