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Welcome to the GitHub page of MERIDA (MEthod for Rule Identification with multi-omics DAta), a tool for drug sensitivity prediction in cancer.

For issues and questions, please contact Kerstin Lenhof (klenhof[at]bioinf.uni-sb.de) If you use MERIDA or the code in this repository, please cite out paper

To install MERIDA, you need to have the following programs/libraries installed:

• Eigen3
• Cplex
• Boost (including the libraries)

If everything is installed, create a build directory, change into the created build directory and issue cmake:

mkdir build cd build cmake -DEIGEN_PATH=/path/to/eigen3 -DCPLEX_PATH=/path/to/cplex ..

MERIDA can be used in two ways:

• Without using the implemented CV functionality: here, a config file and a 'no' as second parameter is required as input (see Example_Config1.txt)
• Using the implemented CV functionality: then a different parameter setting file is required, the second argument is a 'yes' and the third argument is the numer of folds for cross validation (see Example_Config2.txt)