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BHKLAB's Projects

rpharmacodi icon rpharmacodi

R code which enchances the PharmacoDI Python package.

statinemt icon statinemt

Project to regenerate the pharmacogenomics analysis in this paper: "Statin-induced cancer cell death can be mechanistically uncoupled from prenylation of RAS family proteins"

survcomp icon survcomp

R package for performance assessment and comparison for survival analysis

synergxdb icon synergxdb

SYNERGxDB is a comprehensive database to explore synergistic drug combinations for biomarker discovery.

tdgea icon tdgea

Time-dependent gene expression Analysis

toxicodb-web icon toxicodb-web

ToxicoDB is a database of curated toxicogenomics datasets that provides convenient data summary and visualization to mine these complex data. Users can find drug and gene annotations, visualize differential gene expression and enriched pathways within datasets for drug of interest.

toxicogx icon toxicogx

A statistical package, in R, used in cancer research to analyze toxicity of drugs on cancer gene expression across large-scale toxicogenomic datasets.

wci icon wci

Modified Concordance Index for pharmacological readout

xeva icon xeva

XEnograft Visualization & Analysis

xevadb icon xevadb

XevaDB is a database for PDX pharmacogenomic data.

xevadi icon xevadi

The XevaDI is a python package that transforms the CSV files from the Xeva set to create the database table for XevaDB.

zero_interaction_potency-reproduction icon zero_interaction_potency-reproduction

Repository reproducing the original ZIP paper: Yadav, B., et al . (2015). Searching for Drug Synergy in Complex Dose–Response Landscapes Using an Interaction Potency Model. DOI: https://doi.org/10.1016/j.csbj.2015.09.001

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