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Proyecto IAI vaccines - Diplomado UTEC 2021


Repositorio del Proyecto IAI vaccines titulado: "Aplicación de un modelo de aprendizaje no supervisado para la identificación de perfiles en riesgo de hospitalización por efectos adversos causados por la vacuna contra el Covid-19."

Integrantes:

  1. Nicolle Pereira
  2. David Guevera
  3. Leidy Pola
  4. Martina Guillermo
  5. Angel Ramirez
  6. Alvaro Rodríguez
  7. Paulo Vela
  8. Kathy Bolivar
  9. Eduardo Apari

Notas sobre el dataset VAERS


About VAERS.

  • The U.S. Department of Health and Human Services (DHHS) established VAERS, which is co-administered by the Food and Drug Administration (FDA) and the Centers for Disease Control (CDC), to accept all reports of suspected adverse events, in all age groups, after the administration of any U.S. licensed vaccine.
  • The primary purpose for maintaining the database is to serve as an early warning or signaling system for adverse events not detected during pre-market testing.

Careful points about this data set

  1. VAERS data are from a passive surveillance system and represent unverified reports of health events that occur after vaccination.
  2. The event may have been related to an underlying disease or condition, to medications being taken concurrently, or may have occurred by chance.
  3. VAERS data should be used with caution as numbers and conditions do not reflect data collected during follow-up.
  4. Note that the inclusion of events in VAERS data does not infer causality.

About the data codification

  • On 1/17/2007 the VAERS coding system was converted (from an older system: Coding Symbols for a Thesaurus of Adverse Reaction Terms (COSTART) used until 2007) to an international coding system that is used worldwide: Medical Dictionary for Regulatory Activities (MedDRA) which is more detailed.

MedDRA uses key words representing the medical condition(s) described in the case report and converts them to standardized codes. Here this dataset uses more than 17000 "Preferred Terms" MedDRA codes. Codes are updated semi-annually (here on COVID19, we have collected version 23.1 and 24.0).

About the data.

About 85-90% of vaccine adverse event reports concern relatively minor events, such as fevers or redness and swelling at the injection site. The remaining reports (less than 15%) describe serious events, such as hospitalizations, life-threatening illnesses, or deaths.

No data is provided that would allow identification of any individuals associated with these reports.

Data Collection: Based on 2 form versions, online version (on websites) and printing pdf version. Referred on the data set as (VAERS 1 and VAERS 2).

Structure: The downloadable VAERS public data set consists of 3 separate data files.

  1. VAERSDATA.CSV - provides a detailed description of the data provided in each field.
  2. VAERSVAX.CSV - provide the remaining vaccine information (vaccine name, manufacturer, lot number, route, site, and number of previous doses administered), for each of the vaccines listed. VAX_DOSE was discontinued in the VAERS 2 form.
  3. VAERSSYMPTOMS.CSV - provide the adverse event coded terms utilizing the MedDRA dictionary. Each row in the .csv will contain up to 5 MedDRA terms per VAERS ID; thus, there could be multiple rows per VAERS ID. For each of the VAERS_ID’s listed in the VAERSDATA.CSV table, there is a matching record in this file, identified by VAERS_ID, Duplicates may appear in data and terms are listed in alphabetical order. In case a report has more than 5 terms multiple rows with 5 terms each will be listed for that VAERS ID.

Data Types

  1. NUM (float64) = numeric data
  2. CHAR (object) = text or "character" data
  3. DATE (not formated) = date fields in mm/dd/yy format

Data sets merged (total 51 columns)

✔️ # Column Count Dtype Description Notes Options
✔️ # VAERS_ID 591241 float64 VAERS Identification Number Used for merging datasets Unique for DB
✔️ 0 RECVDATE 591241 Datetime Date report was received date
✔️ 1 STATE 535248 object State in the USA 2 letter code nominal
✔️ 2 AGE_YRS 558307 float64 Age in Years integer
3 CAGE_YR 510323 float64 Calculated age of patient in years Needs summation integer
4 CAGE_MO 936 float64 Calculated age of patient in months Needs summation integer
✔️ 5 SEX 591241 object Sex (M, F, Unknown=Blank)
6 RPT_DATE 315 Datetime Date Form Completed REJECTED, low number records date
🤖 7 SYMPTOM_TEXT 591181 object Reported symptom text In Review text
✔️ 8 DIED 9434 object Died Patient Outcomes (Y, Blank)
✔️ 9 DATEDIED 8835 Datetime Date of Death Patient Outcomes date
✔️ 10 L_THREAT 16254 object Life-Threatening Illness Patient Outcomes, Medical history (Y, Blank)
11 ER_VISIT 50 object Emergency Room or Doctor Visit Patient Outcomes VAERS 1 form only (Y, Blank)
✔️ 12 HOSPITAL 53726 object Hospitalized Patient Outcomes (Y, Blank)
✔️ 13 HOSPDAYS 39773 float64 Number of days Hospitalized Patient Outcomes integer
14 X_STAY 418 object Prolongation of Existing Hospitalization Patient Outcomes (Y, Blank)
✔️ 15 DISABLE 13438 object Disability Patient Outcomes, Medical history (Y, Blank)
✔️ 16 RECOVD 541552 object Recovered (Y=recovered, N=not recovered, U=Blank)
✔️ 17 VAX_DATE 564641 Datetime Vaccination Date Check here for vax dosage date
✔️ 18 ONSET_DATE 570860 Datetime Adverse Event Onset Date DOUBLE CHECK HERE date
19 NUMDAYS 548731 float64 Number of days (Onset date - Vax. Date) integer
🤖 20 LAB_DATA 293299 object Diagnostic laboratory data Medical history
✔️ 21 V_ADMINBY 591241 object Type of facility where vaccine was administered VAERS 1.0: PUB=Public, PVT=Private, MIL=Military, OTH=Other, UNK=Unknown. VAERS 2.0: ++ PHM=Pharmacy, SCH=school/student health clinic, SEN=Nursing home or senior living facility, WRK=Workplace clinic.
22 V_FUNDBY 365 object Type of funds used to purchase vaccines VAERS 1 field only PUB=Public, PVT=Private, MIL=Military; OTH=Other/Unknown
🤖 23 OTHER_MEDS 407792 object Other Medications Medical history nominal
🤖 24 CUR_ILL 328851 object Illnesses at time of vaccination Medical history nominal
🤖 25 HISTORY 422557 object Chronic or long-standing health conditions Medical history, VAERS 1 form only, this field also includes pre-existing physician-diagnosed allergies nominal
🤖 26 PRIOR_VAX 36239 object Prior Vaccination Event information Medical history nominal
27 SPLTTYPE 98610 object Manufacturer/Immunization Project Report Number REJECTED, not on the scope nominal
28 FORM_VERS 591241 int64 VAERS form version 1 or 2 (1, 2)
29 TODAYS_DATE 588302 Datetime Date Form Completed Not relevant REJECTED date
30 BIRTH_DEFECT 406 object Congenital anomaly or birth defect Patient Outcomes, Medical history. Only in VAERS2 (Y, Blank)
31 OFC_VISIT 136672 object Doctor or other healthcare provider office/clinic visit Patient Outcomes,Only in VAERS2 (Y, Blank)
✔️ 32 ER_ED_VISIT 103144 object Emergency room/department or urgent care Patient Outcomes,Only in VAERS2 (Y, Blank)
🤖 33 ALLERGIES 381752 object Allergies to medications, food, or other products nominal
34 SYMPTOM1 591241 object Adverse Event MedDRA Term 1 code
35 SYMPTOMVERSION1 591241 float64 MedDRA dictionary version number 1 code
36 SYMPTOM2 470315 object Adverse Event MedDRA Term 2 code
37 SYMPTOMVERSION2 470315 float64 MedDRA dictionary version number 2 code
38 SYMPTOM3 367938 object Adverse Event MedDRA Term 3 code
39 SYMPTOMVERSION3 367938 float64 MedDRA dictionary version number 3 code
40 SYMPTOM4 279936 object Adverse Event MedDRA Term 4 code
41 SYMPTOMVERSION4 279936 float64 MedDRA dictionary version number 4 code
42 SYMPTOM5 207749 object Adverse Event MedDRA Term 5 code
43 SYMPTOMVERSION5 207749 float64 MedDRA dictionary version number 5 code
44 VAX_TYPE 591241 object Administered Vaccine Type (Many, only COVID19 interested)
✔️ 45 VAX_MANU 591241 object Vaccine Manufacturer important (Many, only COVID19 interested)
✔️ 46 VAX_LOT 419626 object Manufacturer's Vaccine Lot double check (Many, only COVID19 interested)
✔️ 47 VAX_DOSE_SERIES 588217 object Number of doses administered Not completely reliable, The VAERS 1 field VAX_DOSE was discontinued in the VAERS 2 (1 --if it was noted -- , Blank)
✔️ 48 VAX_ROUTE 464076 object Vaccination Route Could be important.. (UN=Unknown, ID=Intradermal, IM=Intramuscular, SC=Subcutaneous, IN=Intranasal, PO=Per Oral, SYR=Needle and syringe (not specified further), JET=Needle free jet injector device,OT=Other)
✔️ 49 VAX_SITE 476756 object Vaccination [Anatomic] Site nominal
50 VAX_NAME 591241 object Vaccination Name REJECTED === VAX_MANU (Many, only COVID19 interested)

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