$ pip install dataframe-mapper

from dfmapper import DataFrameMapper, IntColumn, StrColumn

class UserDfm(DataFrameMapper):

    id = IntColumn(min=1, nullable=False)
    username = StrColumn(max_length=30, nullable=False)
    profile = StrColumn()

    def find_by_id(self, id):
        return self.df[self.df.id == id]

user_dfm = UserDfm({
    "id": [1, 2, 3],
    "username": ["Bessie Bennett", "Sandra Matthews", "Jessie Bates"],
    "profile": ["BLAH BLAH BLAH", "PITH PITH PITH", None]
})

user_dfm.is_valid()
#: True

user_dfm.find_by_id(1)
#:    id username       profile
#: 0  1  Bessie Bennett BLAH BLAH BLAH