Using CubSFS to get demographic reconstructions of a population using an SFS (allele/site frequency spectrum)

What the heck is an SFS?

By the end of today you will:

1. Be able to install R Studio and manually install an R package
2. Know how to source R functions within R Studio
3. Read in an SFS file into R
4. Run a CubSFS analysis
5. Evaluate whether results are valid based on knot placement, bootstrap, and QC metrics.
6. Plot the data

Head to the instructions for getting started

CubSFS paper:
Waltoft, B.L. and Hobolth, A., 2018. Non-parametric estimation of population size changes from the site frequency spectrum. Statistical applications in genetics and molecular biology, 17(3). https://www.degruyter.com/document/doi/10.1515/sagmb-2017-0061/html

CubSFS tutorial:
https://htmlpreview.github.io/?https://raw.githubusercontent.com/blwaltoft/CubSFS/master/CubSFS.html

CubSFS github:
https://github.com/blwaltoft/CubSFS