-IvanWoo-'s Projects
My configuration files on MacOS.
It's my graduation project at NJU with the help of professor WangQ.
A brand new version of MgR_seq.
A toolkit created for some bioinformatics work.
configuration on Ubuntu 14.04.5LTS
RNase R is a member of the RNA exonuclease family that digests RNA from 3′ to 5′. Previous studies have identified RNase R from Mycoplasma genitalium (MgR) as its only RNA exonuclease, which is sensitive to Nm modification. However, the mechanism of this characteristic is not well understood. In this study, we aimed to explore the molecular mechanism of RNase R Nm sensitivity with the help of a newly established quantitative assay, which excluded the effect of hydrolytic activity. By comparing five wild-type RNase R from Mycoplasma, we indicated the importance of loop 18 in Nm sensitivity. Furthermore, we demonstrated the critical roles of L283, T278, and T279. This study deepened the molecular mechanism of the Nm sensitivity of MgR and provided the potential direction of protein engineering for application.
Try different ways to identify segmental duplications.
My config on APHID.
egaz and alignDB work with external (NCBI/EBI) data
Some (original or reposted) blogs.