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enrichr_cli

Python script to query enrichr from command line (http://amp.pharm.mssm.edu/Enrichr/)

###Required python libraries:

  • json
  • requests
  • sys
  • os

###Input Input is a newline-separated list of gene symbols, either from a file or on stdin.

###Usage

  • python enrichR.py genelist.txt [using default databases, see further]
  • python enrichR.py genelist GO_Molecular_Function_2015 [using just one database]
  • python enrichR.py genelist GO_Molecular_Function_2015 Reactome_2016 [using just two databases]
  • cat genelist.txt | python enrichR.py - [reading from a pipe]

###Output: Per used database a file will be created containing the enrichment results.

###Databases To get a list of all available databases: python enrichR.py databases

Default databases, used without specifying a database:

  • KEGG_2015
  • BioCarta_2016
  • WikiPathways_2016
  • Reactome_2016
  • GO_Biological_Process_2015
  • GO_Cellular_Component_2015
  • GO_Molecular_Function_2015
  • MSigDB_Computational
  • Panther_2016

#####Notes

  • The databases are hardcoded in the script and as such will not follow updates from Enrichr automatically.
  • If you specify a database which is not available you will receive a warning.
  • If not a single valid database is specified the default set will be used.

I'm not affiliated to the authors of Enrichr but just use their API.

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