Copyright 2018

SBML Solver is high performance and portable simulation engine for systems and synthetic biology, which is a continuation of the original libRoadRunner project.

• Time Dependent Simulation (with optional conservation law reduction) using CVODE
• Supports SBML Level 2 to 3 but currently excludes algebraic rules and delay differential equations
• Uses latest libSBML distribution
• Defaults to LLVM code generation on the backend, resulting is very fast simulation times
• Optional generation of model C code and linking at run-time
• Add plugins, distribution comes with Levenberg-Marquardt optimizer plugin
• Compute steady state
• Metabolic Control Analysis
• Frequency Domain Analysis
• Access to:
  • Eigenvalues and Eigenvectors
  • Jacobian, full and reduced
  • Structural Matrices of the stoichiometry matrix

SBML Solver is licensed for free as an open source programmatic library for use in other applications and as a standalone command line driven application. Its C++ API, C API, and Python APIs have comprehensive documentation. On Windows, OS X, and Linux binary files can be

downloaded from https://github.com/AndySomogyi/sbmlsolver ready for use.

This work is funded by NIGMS grant: GM081070

Licence

Licensed under the GNU Library General Public License (LGPL), Version 2.0 (the License); you may not use this file except in compliance with the License. You may obtain a copy of the License at

YOU CANNOT: redistribute any piece of this software without proper attribution;