Toni Giorgino (IBF-CNR), www.giorginolab.it.
To access "live" notebooks containing various takes on MSM calculations, in R and Python, see https://github.com/giorginolab/Markov-Tutorial-Data
See also this Colab notebook which shows how to implement the same calculations in the DeepTime library.
For different takes, see the giorginolab organisation repositories.