This code is associated with the paper from de Freitas Nascimento et al., "Codon choice directs constitutive mRNA levels in trypanosomes". eLife, 2018. http://dx.doi.org/10.7554/eLife.32467
MCMC method for estimating geCAI codon weights from CDS and mRNA abundance data
geCAI.pl -i <SEQUENCE_FILE> -e <EXPRESSION_FILE>
OPTIONS:
-i <file> FASTA format file containing multiple CDS sequences
-e <file> Tab-delimitted text file of abundance estimates for CDS
-g <int> Number of generations for MCMC [Default = 5000]
-p <int> Print frequency [Default = 100]
-w <file> Specify staring codon weights [Defualt = random]
Package contains example sequence and mRNA files. To run geCAI on these files execute
geCAI.pl -i Example_Sequences.fasta -e Example_Expression_Data.txt
Distributed under the GNU General Public License (GPLv3). See License.md
When publishing work that uses geCAI please cite: Nascimento & Kelly et al. (2018)