tox-uv is a tox plugin which replaces virtualenv and pip with uv your tox environments. Note that you will get both the benefits (performance) or downsides (bugs) of uv.

Install tox-uv into the environment of your tox and will replace virtualenv and pip for all runs:

python -m pip install tox tox-uv
python -m tox r -e py312 # will use uv

• uv-venv-runner is the ID for the tox environments runner.
• uv-venv-pep-517 is the ID for the PEP-517 packaging environment.
• uv-venv-cmd-builder is the ID for the external cmd builder.

This flag, set on a tox environment level, controls if the created virtual environment injects pip/setuptools/wheel into the created virtual environment or not. By default, is off. You will need to set this if you have a project that uses the old legacy editable mode, or your project does not support the pyprooject.toml powered isolated build model.