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Muller diagrams excel at visualizing evolutionary dynamics of a population over time. A common use case, and the intended use case during development, describes the abundance and succession of genotypes within a population derived from sequencing data from samples at specified timepoints. This provides a useful method of quickly discerning the evolutionary relationship between genotypes seen in a population and how this changes over time.

License: MIT License

Python 88.61% R 11.39%

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lolipop's Issues

Total frequency larger than 100% of the last time point, inaccurate genotype inference

We used lolipop in our poject, we found that the total frequency of genotypes in the last time point is larger than 100% (150), it is reasonable, there would be something wrong in the genotypy inference or clustering. Another question is one genotype is wrongly nested according to the isolate data, we can use the "-g" to calibrate it. While the frequency problem is still there.

Scripts

The current version outputs a folder "scripts" that is empty. Previous versions had at least an r script here to allow easy alteration of ggmuller parameters. Would be nice to have that output again.

errors when running lollipop lineage

I followed instructions to install - generating a conda environment for the required packages and installing lollipop through pip. I ran pip install lolipop --upgrade and lolipop lineage -h and all looked OK. When I tried running with an --input as my own CSV file the script broke. The cause of the problem seems to be FileNotFoundError: [Errno 2] No such file or directory: 'seaborn-white'

TypeError: can only concatenate str (not "int") to str

When installing lolipop (pip install lolipop, Python version 3.9) in a conda virtual environment on Ubuntu 22.04 LTS, I encountered an error when running the example data from the user guide. See error.txt for the detailed error message.
error.txt
Looking forward to your reply, thank you!

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