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BioMASS is a computational framework for modeling and analysis of biological signaling systems in Python.

• Documentation: https://biomass-core.rtfd.io
• Source code: https://github.com/biomass-dev/biomass
• Bug reports: https://github.com/biomass-dev/biomass/issues
• Citing in your work: https://biomass-core.rtfd.io/en/latest/citing.html

It provides useful tools for numerical simulation, parameter estimation, network analysis, and result visualization.

The BioMASS library is available at the Python Package Index (PyPI).

$ pip install biomass

BioMASS supports Python 3.8 or newer.

• Imoto, H., Zhang, S. & Okada, M. A Computational Framework for Prediction and Analysis of Cancer Signaling Dynamics from RNA Sequencing Data—Application to the ErbB Receptor Signaling Pathway. Cancers 12, 2878 (2020). https://doi.org/10.3390/cancers12102878

• Imoto, H., Yamashiro, S. & Okada, M. A text-based computational framework for patient -specific modeling for classification of cancers. iScience 25, 103944 (2022). https://doi.org/10.1016/j.isci.2022.103944

• Arakane, K., Imoto, H., Ormersbach, F. & Okada, M. Extending BioMASS to construct mathematical models from external knowledge. Bioinformatics Advances 4, vbae042 (2024). https://doi.org/10.1093/bioadv/vbae042

Hiroaki Imoto

Apache License 2.0