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orn-analysis

Adult (3-10 day) Drosophila ORN snRNAseq neuropeptide and neuropeptide receptor expression analysis

  • All sequence data was generated by Li Lab
  • Y-axis: barcoded cells grouped by which glomeruli it innervates in AL
  • X-axis: Drosophila neuropeptide/neuropeptide receptor gene expression of grouped cells
  • Interestingly, V (carbon dioxide circuit) cells are positive for sNPF expression and also for receptors AstA-R1, AstC-R2, Dh44-R1, MsR1, NPFR, Pdfr, SPR
  • ORN-ORN feedback modulation?
  • The presence and abundance of these specific receptors in transcripts from nuclei of ORNs that innervate CO2 glomerulus may have a role in the olfactory processing of CO2 and ultimately behavior
Screenshot 2023-12-04 at 12 44 42 PM Screenshot 2023-12-04 at 12 45 08 PM

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