Name: Spakowicz Lab
Type: Organization
Bio: OSU academic research lab studying how the microbiome interacts with the immune system, particularly as it relates to cancer and response to immunotherapies
Location: The Ohio State University
Blog: https://u.osu.edu/spakowiczlab/
Spakowicz Lab's Projects
Intratumoral microbes correlate with tumor-infiltrating lymphocytes in lung cancer RNAseq
Script for predicting the completion date of clinical trials
The effect of co-morbidities on immunotherapy response.
Code to reproduce the analyses described in the manuscript, "Approaches for integrating heterogeneous RNA-seq data reveals cross-talk between microbes and genes in asthmatic patients"
Code to support the study of diabetic complications using preclinical models
Code related to the study of the tumor microbiome and head and neck cancer
Code for processing and analyses associated with the recrad project
Make functions utilized in the exotic pipeline available through package format
code related to data processing and analysis for exotic manuscript
analysis related to the FITNESS Study at OSU
Coding and structure conventions in the lab
Microbiome, Aging and Immunotherapy
R Shiny app to support the use of mobile health data in academic clinical trials. This tool enables one to obtain consent to share user's FitBit data with the research team.
This package contains functions to calculate microbe signatures, particularly from bugsigdb inputs.
Power, data processing and analyses related to the "modbio" companion to the INSIGNA clinical trial
R package for a multi-threshold survival area analysis
Analyses and calculations related to the study of NKTcells in cancer
Analysis associated with the publication, "Change in neutrophil to lymphocyte ratio during immunotherapy treatment is a non-linear predictor of patient outcomes in advanced cancers" DOI : 10.1007/s00432-019-02982-4
Spakowicz lab methods for sequencing microbiome & other samples
Tumor Microenvironment expression signatures