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Hi there, I'm Kamil 👋

I work as a biomedical researcher at Mass General Brigham, where I focus on statistical analysis for projects that involve millions of cells from hundreds of patient samples.

My research experience is in the fields of human genetics, functional genomics, and immunology. I specialize in the analysis of single-cell transcriptomics data (scRNA-seq).

In other words, I study data that tells us what cells are doing at the molecular level, and I compare the cells from different people to find out what might be happening in the context of diseases like rheumatoid arthritis, immunotherapy-related colitis, and COVID-19.

I also have research experience in human genetics, with a focus on immunology and the human leukocyte antigen (HLA) genes.

Single cell RNA-seq data

170k cells from 350 patients. Each point represents a cell. Color represents a cell's assignment to a cluster of cells, based on its similarity to other cells. Each cell is embedded in 3 dimensions based on its gene expression profile. (Make your own animation in R.)

Harmony can help to integrate many batches of high-dimensional data (R package or Python package).

A human HLA-TCR complex (6py2)

Two human proteins. The HLA protein (pink and purple subunits) is at the bottom and it is presenting a peptide (green) to the TCR protein (orange and yellow subunits) on top. The peptide is a fragment of the glutenin protein from wheat flour. This presentation mechanism is the basis for our adaptive immunity that protects us from pathogens and cancers, but it can also make us susceptible to autoimmune diseases.

Find tools and databases for analyzing HLA and VDJ genes at slowkow/awesome-vdj.

Kamil Slowikowski's Projects

altocumulus icon altocumulus

Command line utilities for running workflows on Terra

arrayqc icon arrayqc

Quality control metrics for microarray data.

awesome-single-cell icon awesome-single-cell

List of software packages for single-cell data analysis, including RNA-seq, ATAC-seq, etc.

awesome-vdj icon awesome-vdj

📚 Tools and databases for analyzing HLA and VDJ genes.

baseapp icon baseapp

Bootstrap-based web application scaffolding built in Go on top of the Revel Web Framework w/ Docker build support

blog icon blog

Source code of my personal blog

bryozoa icon bryozoa

Automatically exported from code.google.com/p/bryozoa

btcd icon btcd

An alternative full node bitcoin implementation written in Go (golang)

cellbrowser icon cellbrowser

Python pipeline and Javascript scatter plot library for single-cell datasets

cellguide icon cellguide

🧭 Navigate single-cell RNA-seq datasets in your web browser.

corshrink icon corshrink

R package for adaptive correlation and covariance matrix shrinkage.

covid-stats icon covid-stats

New daily Covid cases and deaths in USA. Data from usafacts.org

custard icon custard

:custard: Find overabundant profiles in time series gene expression data.

ddrtree icon ddrtree

An R implementation of the DDRTree algorithm for learning principal graphs

demuxem icon demuxem

Demultiplexing cell/nucleus hashing data for single-cell genomics

edge icon edge

R package for identifying differentially expressed genes from genome-wide gene expression profiling studies.

ffbase icon ffbase

Basic (statistical) functionality for R package ff

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