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Marta Spreafico, PhD's Projects

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Modelling time-varying covariates effect on survival via functional data analysis: application to the MRC BO06 trial in osteosarcoma.

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Longitudinal Latent Overall Toxicity (LOTox) profiles in osteosarcoma: a new taxonomy based on latent Markov models.

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Dynamic monitoring of the effects of adherence to medication on survival in heart failure patients: A joint modelling approach exploiting time-varying covariates.

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Code for implementing a Joint Model of recurrent and terminal events with Discretely-distributed non-parametric Frailty.

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Functional modeling of recurrent events on time-to-event processes.

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Positivity violations in marginal structural survival models with time-dependent confounding: a simulation study on IPTW-estimator performance.

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Code for assessing the causal effects of chemotherapy Received Dose Intensity (RDI) on survival outcomes in osteosarcoma patients using a Target Trial Emulation approach.

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