[wow64] error with checking about protontricks HOT 1 OPEN

The first two are Winetricks related issues.

• "Unknown file arch 65" is being tracked at Winetricks/winetricks#2183. The warnings can be safely skipped and they don't affect functionality besides the popups being annoying.
• SHA256 mismatches happen occasionally when Microsoft updates their binaries. Winetricks updates the SHA256 sums every now and then to match the upstream binary but this is a moving target. You might have better luck if you forego the Arch packaging of Winetricks and install the latest development version using instructions here.

As for the path being at ~/.local/share/wineprefixes instead of at the Steam game's compatdata directory, can you try launching it using protontricks -vv <appid> -v --gui instead and posting the output to gist.github.com? Replace <appid> with the app ID of the game that has the issue; you can see the app ID in the game selection dialog. This should hopefully give a better idea of what's happening.

from protontricks.