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MartinFXP avatar MartinFXP commented on September 2, 2024

Since I did not author this package (I just parallelized it and improved speed in general), I do not know (or remember) how the authors decided for the selected genes. But you can look into the original package page and the publication. The corresponding links are at the bottom of the readme.

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LiuYangyang-math avatar LiuYangyang-math commented on September 2, 2024

Since I did not author this package (I just parallelized it and improved speed in general), I do not know (or remember) how the authors decided for the selected genes. But you can look into the original package page and the publication. The corresponding links are at the bottom of the readme.

Thanks a lot for your reply! I have read the original paper, package manual file and the readme file very carefully, but author didn't mention it. And the method of select genes is important for our work now, we checked a lot of information but no clue, that's why I'm confused about this. I'm very sorry for my rude behavior ,but would you tell me that how to contact the author, I cannot contact the author(the email in the paper is fail), very thanks!

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MartinFXP avatar MartinFXP commented on September 2, 2024

I'm sorry, but I do not have more information than stated in the readme.

In general you do not have to select for genes before using dawnrank. After all dawnrank does the ranking for you. Of course you can select for genes which are differentially expressed between normal and cancer tissue or select genes which have a high variability. Those are standard approaches for gene selection.

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