Algorithm to impute missing age information about pedsuite HOT 4 CLOSED

Hi,
That's an interesting question. Nothing like that is implemented in the ped suite currently, and I cannot recall having seen it elsewhere either. I'd be interested in knowing what you come up with, though!

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Thanks for your reply. If I am going to write an R function for this, what pedsuite package can I use to load the pedigree, easily access someone's parents and siblings and their information, and save the pedigree back?

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Within the ped suite framwork, pedigrees are represented as ped objects, which contains the pedigree info and (optionally) marker genotypes. Pedigrees can be loaded from "ped" files with readPed() or built from scratch. The pedtools vignette has some examples: https://cran.r-project.org/web/packages/pedtools/vignettes/pedtools.html

Once you have a pedigree, you can find identify all kinds of relatives, e.g.:

library(pedtools)

# Pedigree with 3 sibs
x = nuclearPed(3)
x
#>  id fid mid sex
#>   1   *   *   1
#>   2   *   *   2
#>   3   1   2   1
#>   4   1   2   1
#>   5   1   2   1
parents(x, 3)
#> [1] "1" "2"
father(x, 3)
#> [1] "1"
siblings(x, 3)
#> [1] "4" "5"

The ped class does not store age information or other clinical data, so you would have to keep these in a separate container.

from pedsuite.

Thank you very much!

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