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loucerac's Projects

dmaps icon dmaps

Placeholder for common development on hipathia and disease maps.

drexml icon drexml

(DRExM³L) Drug REpurposing using eXplainable Machine Learning and Mechanistic Models of signal transduction

dualaae-ehr icon dualaae-ehr

Dual Adversarial Autoencoder for Generating Set-valued Sequences

geometric_ml icon geometric_ml

This repository contains code for applying Riemannian geometry in machine learning.

gin icon gin

Graph Intervention Networks (GIN) (NeurIPS 2021)

gp_extras icon gp_extras

Additional kernels that can be used with scikit-learn's Gaussian Process module

high-dimensional-model-explanations-an-axiomatic-approach icon high-dimensional-model-explanations-an-axiomatic-approach

Complex black-box machine learning models are regularly used in critical decision-making domains. This has given rise to several calls for algorithmic explainability. Many explanation algorithms proposed in literature assign importance to each feature individually. However, such explanations fail to capture the joint effects of sets of features. Indeed, few works so far formally analyze high dimensional model explanations. In this paper, we propose a novel high dimension model explanation method that captures the joint effect of feature subsets. We propose a new axiomatization for a generalization of the Banzhaf index; our method can also be thought of as an approximation of a black-box model by a higher-order polynomial. In other words, this work justifies the use of the generalized Banzhaf index as a model explanation by showing that it uniquely satisfies a set of natural desiderata and that it is the optimal local approximation of a black-box model. Our empirical evaluation of our measure highlights how it manages to capture desirable behavior, whereas other measures that do not satisfy our axioms behave in an unpredictable manner.

luad_lusc_tcga_comparison icon luad_lusc_tcga_comparison

Scripts and Data associated with our publication on genomic signatures to discriminate LUAD and LUSC lung cancer types using TCGA data

malmstin icon malmstin

Unveiling the Druggable Landscape: A Multimodal Approach (MALMSTIN)

pybel icon pybel

A pure Python package for parsing, validating, compiling, and converting biological knowledge graphs encoded in BEL

rnn-vae icon rnn-vae

Hybrid prediction system. Use VAE to get latent states of a time-dependent system. Use RNN (Reservoir Computer) to evolve latents. VAE translates to predictions

scibet icon scibet

A portable and fast single cell type identifier

scmatch icon scmatch

scMatch: a single-cell gene expression profile annotation tool using reference datasets

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