Comments (1)
The current, built-in version does tend to be slower than the ropebwt2 approach for constructing the BWT. This is most noticeable for short-read sequencing data, where ropebwt2 can take advantage of parallelization during some of the inserts. The downside of this approach is that the commands to construct it are a bit more complicated and may require excess memory/disk space to do the sorting.
The msbwt2 construction is primarily meant to make the process (e.g. the commands) a bit easier for end users who may not be as CLI familiar. We would like to make this method faster (perhaps via parallelization and/or a better algorithm), but we haven't had time to work on this. It also may not scale as well, we haven't really tested a very large dataset yet. Happy to review PRs from anyone wishing to do R&D on improving the method.
So in short, if you want speed, we recommend using the ropebwt2 approach. If you want ease of use, we recommend the msbwt2 approach.
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