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havakv avatar havakv commented on August 23, 2024 3

Great work! It looks good. I've also realised that I might not have much time in the foreseeable future to work on this. But if I can find the time, I'll ask for your opinion on the code.

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havakv avatar havakv commented on August 23, 2024 1

Hi, the Deep Survival Machines are a very interesting approach and I think they would be a very nice addition to pycox. I'm on vacation for the next couple of weeks, so I probably want be able to look into it before I'm back, but you are more than welcome to start on a pull request.

I haven't fully comprehended the details of the DSM, but a reasonable place to start would be to put the loss functions in loss.py and create a model class that contains the necessary logic for training and prediction. Mostly, methods only need a defined loss and a predict_surv method (e.g., LogisticHazard) but the DSM probably need something extra for the pre-training? As far as I can understand, you shouldn't need to worry about data loaders, but you should probably include an example network to show how the method works.

I understand that they way pycox is build on torchtuples can make it strange to build a model (probably some things there I should have changed...) so I can only encourage you to try to look at some of the methods and see if you can find a reasonable way to rewrite DSM in this manner. If something is unclear, you shouldn't hesitate to ask me, and I'll try to assist you! Does this sound reasonable?

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CamDavidsonPilon avatar CamDavidsonPilon commented on August 23, 2024

I have no involvement in PyCox (just a passive observer ;), but I looked over that paper. Cool stuff @chiragnagpal! I really like the graphical abstract in Fig 1.

EDIT: oh, but is it really correct to say that Cox has a constant baseline hazard, in the Abstract? Should it be "constant proportional hazard?"

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chiragnagpal avatar chiragnagpal commented on August 23, 2024

@CamDavidsonPilon Thanks for giving it a read... you're right, what we really mean is constant proportional hazards...

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havakv avatar havakv commented on August 23, 2024

@chiragnagpal have you started on this? Do you need any help with this?

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chiragnagpal avatar chiragnagpal commented on August 23, 2024

Hi we released a reasonably well documented package with the deep survival machines model here: https://autonlab.github.io/DeepSurvivalMachines . At this stage I do not have enough bandwidth to reepackage it to. be compatible with pycox, folks interested in experimenting with dsm can use our package.

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