Comments (4)
The current model structure is chosen with reference to empirical findings from the Covid-19 pandemic, that vaccinated individuals are less likely to be infected, and less likely to suffer adverse outcomes from infection (hospitalisation and death).
This model structure could be simplified in two different ways:
- Two-dose vaccination only reduces the rate at which individuals are infected (
$\beta$ by a factor), but has no effect on further infection compartment transitions; - Two-dose vaccination reduces all transition rates by a uniform factor;
- Removing the H, ICU, and D compartments which may not add much information and which could be estimated separately from known conversion rates. The H compartment might become important for outbreaks where hospitalisation also indicates quarantine, as these individuals are no longer available to infect others.
Conversely the model could be made more complex to reflect that:
- Some vaccinated individuals might never become infectious, and transition directly to the recovered compartment;
- The mortality rate increases when individuals enter more serious healthcare compartments (e.g. ICU > H > I).
from epidemics.
Hi @bahadzie I'm just reopening this issue - the idea with the "Discussion" issues is that they remain open even when they're marked as done.
from epidemics.
Apologies @pratikunterwegs I thought I clicked on the dropdown arrow next to the 'Close with comment' button to see what other options were available.
from epidemics.
Closing as this model is stable.
from epidemics.
Related Issues (20)
- Enhance `epidemic_size()`
- Improve input checking and cross-checking HOT 2
- Fix URL for pkgdown website
- Document how to make simple, developer-side model edits HOT 4
- Add vignette for combined vacccination and intervention scenarios HOT 1
- Dynamic updating of vaccination rate
- Potential discrepancy in epidemic sizes HOT 2
- Remove Not Published from repo description? HOT 1
- Release epidemics 0.3.0 HOT 1
- Possible scenario comparison functionality HOT 3
- Default model with odin-backend example HOT 14
- Linking compiled {odin} code with {epidemics} HOT 1
- new infections curve is interrupted when using vaccination HOT 3
- Vaccination counts lead to negative susceptibles HOT 1
- Allow time-varying, age-specific vaccination rates HOT 1
- Consider allowing reinfections in models
- Reconsider two-stage vaccination for Vacamole
- Feedback on diphtheria/camps model
- Add basic SIR model HOT 1
- Release epidemics 0.4.0
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