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šŸ‘‹ Hi, Iā€™m Claudio Lorenzi ( @CloXD ): Bioinformatician, full stack software developer interested in Machine Learning and Artificial Intelligence.

Visit my webpage to know more about me!

You can find some of my works here:

  • PCaProfiler: the Prostate Cancer atlas Profiler, the web tool that enables you to mine clinical and transcriptional data of over 1365 clinical samples across various stages. Associations with prostate cancer progression can be quantified using a quantitative pseudotime progression score. In addition, the tool also allows the annotation of new experimental and clinical data for disease progression.
  • iMOKA: a tool to identify k-mers as classifing features from large datasets of sequencing data. The software is mainly written in C++ ( MLPack as ML library ) and Pyhton ( scikit-learn and TF libraries ) for the core part and Angular + Electron for the GUI.
  • IRFinder-S: a new version of the popular software for the identification and quantification of intron retention events. Includes a CNN based filter that discerns artefactual IR events using visual-like features ( TensorFlow Python library) and a IR database/visualization web tool, IRbase
  • MAGeCK_View: a small web page that allows to visualize the results of CRISPR screening generated by MAGeCK.
  • Cell2Patients: I contributed to my colleague's PhD project that aim to transfer the knowledge aquired from cell lines model to patient data
  • PickPocket: an attempt to create an automatic protein pocket classifier that uses secondary structure informations alongside with other useful features. Unfortunately, our tests didn't show a real improvement respect to other existing methods, but it was a good attempt.

Claudio Lorenzi's Projects

cell2patients icon cell2patients

Transfer learning from cell lines biological data to patients

chipseq icon chipseq

ChIP-seq peak-calling, QC and differential analysis pipeline.

cloxd icon cloxd

Config files for my GitHub profile.

ctat-mutations icon ctat-mutations

Mutation detection using GATK4 best practices and latest RNA editing filters resources. Works with both Hg38 and Hg19

cutandrun icon cutandrun

Analysis pipeline for CUT&RUN and CUT&TAG experiments that includes QC, support for spike-ins, IgG controls, peak calling and downstream analysis.

cxxopts icon cxxopts

Lightweight C++ command line option parser

igv.js icon igv.js

Embeddable genomic visualization component based on the Integrative Genomics Viewer

modules icon modules

Repository to host tool-specific module files for the Nextflow DSL2 community!

sarek icon sarek

Analysis pipeline to detect germline or somatic variants (pre-processing, variant calling and annotation) from WGS / targeted sequencing

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