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chrchang avatar chrchang commented on September 25, 2024

The lower-MAF SNP is pruned. If the MAFs are equal, the later-position SNP is pruned.

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KehaoWu avatar KehaoWu commented on September 25, 2024

Is it possible that incorporate p values or function information into SNP prunning?
For example, the smaller p-value SNP is pruned. If the p-values are equal, the intergenic SNP is pruned.

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chrchang avatar chrchang commented on September 25, 2024

You can currently get this behavior by creating an artificial set of "MAF estimates" which are a function of p-value and gene positions, and loading that with --read-freq. (Just make sure to not include any filters which actually depend on MAF in your run...)

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KehaoWu avatar KehaoWu commented on September 25, 2024

Good idea! Thank you!

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