Comments (5)
@mbrush I believe we were going with correlated_with as the grouping predicate and would allow for various types of correlation contexts, e.g. in the literature
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@cmungall I would consider a new relation specific for correlated mentions, which could potentially live under 'correlates_with'. If we use the parent 'correlated_with' for literature-co-occurrence, we may end up with assertions in our KGs about correlations between entities like chemicals and diseases where some describe correlation of the actually entities in biological setting, and others that describe correlated occurrence in the literature. e.g. HER2 and breast cancer may be correlated biologically, and their mentions in the literature may also be correlated. We need to be able to distinguish between these cases.
I might propose a correlated_with sub-property to handle the literature co-occurrence - perhaps something like 'mentions_correlated_with'. Or maybe it doesn't even make to have this be a correlated_with subproperty - as the entities represented by the subject and object of this predicate in a KG (e.g. a variant and disease) don't themselves correlate with each other in the way that the correlated_with predicate is defined (from RO: "A relationship that holds between two entities, where the entities exhibit a statistical dependence relationship. The entities may be statistical variables, or they may be other kinds of entities such as diseases, chemical entities or processes.")
Curious what peoples thoughts are here.
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Is this still relevant?
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I'm going to assign this to the predicates WG - thanks @nlharris! :)
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Right now in the model, @cbizon - we have 'correlated with' (as per @cmungall's proposal above), which specifies namedthing and namedthing as domain/range specifically. There are also several children of correlated with in the model that might address some of @mbrush's concerns. I am going to close this case (please definitely reopen if I missed a use case).
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Related Issues (20)
- GeneAffectsChemicalAssociation with qualifiers HOT 1
- Undeprecate RWE predicate
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- New predicate request for micro-organisms <=> media HOT 4
- Promote GenomicEntity to be a concrete class instead of a mixin HOT 5
- Add biolink model purl to top level README HOT 3
- Add a public visibility tag to mixins HOT 2
- Biolink Model "Cookbook" or ... HOT 1
- representing strains/variants
- representing active metabolites HOT 2
- additional aspect qualifiers HOT 2
- representing components that can be present in complex mixture
- Improve formulation of PMC in prefix map HOT 1
- Should `OrganismTaxon` be a child of `OrganismalEntity` ? HOT 2
- schema fails linkml validation HOT 2
- NCIT prefix should be defined in the biolink-model.yaml `prefixes` section HOT 3
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